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human anti rabbit monoclonal cdk4 antibody  (Cell Signaling Technology Inc)
96
Cell Signaling Technology Inc human anti rabbit monoclonal cdk4 antibody
Figure 2. P16INK4A‑CDK4 interaction is upregulated in SiHa‑DDP cells with pRb inactivation. (A) Western blot analysis revealed the changes in P16, cyclin D1 and pRb protein expression, indicating an inverse cor relation with P16 and cyclin D1, pRb in DDP‑resistant SiHa‑DPP cells. (B) Co‑immunoprecipitation was conducted to evaluate the enhanced interaction between P16 and <t>CDK4</t> in SiHa‑DDP cells when compared with SiHa cells. DDP, cisplatin; Rb, retinoblastoma protein; pRb, phosphorylated retinoblastoma protein; CDK, cyclin‑dependent kinase.
Human Anti Rabbit Monoclonal Cdk4 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cdk4+12790/CDK4+Rabbit+mAb/pm25663864-52-30-35
Average 96 stars, based on 1 article reviews
human anti rabbit monoclonal cdk4 antibody - by Bioz Stars, 2026-10
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Figure 2. P16INK4A‑CDK4 interaction is upregulated in SiHa‑DDP cells with pRb inactivation. (A) Western blot analysis revealed the changes in P16, cyclin D1 and pRb protein expression, indicating an inverse cor relation with P16 and cyclin D1, pRb in DDP‑resistant SiHa‑DPP cells. (B) Co‑immunoprecipitation was conducted to evaluate the enhanced interaction between P16 and CDK4 in SiHa‑DDP cells when compared with SiHa cells. DDP, cisplatin; Rb, retinoblastoma protein; pRb, phosphorylated retinoblastoma protein; CDK, cyclin‑dependent kinase.

Journal: Oncology letters

Article Title: P16 INK4A is required for cisplatin resistance in cervical carcinoma SiHa cells.

doi: 10.3892/ol.2014.2814

Figure Lengend Snippet: Figure 2. P16INK4A‑CDK4 interaction is upregulated in SiHa‑DDP cells with pRb inactivation. (A) Western blot analysis revealed the changes in P16, cyclin D1 and pRb protein expression, indicating an inverse cor relation with P16 and cyclin D1, pRb in DDP‑resistant SiHa‑DPP cells. (B) Co‑immunoprecipitation was conducted to evaluate the enhanced interaction between P16 and CDK4 in SiHa‑DDP cells when compared with SiHa cells. DDP, cisplatin; Rb, retinoblastoma protein; pRb, phosphorylated retinoblastoma protein; CDK, cyclin‑dependent kinase.

Article Snippet: The membranes were then incubated with human anti-mouse monoclonal p16 antibody (Sigma-Aldrich, St. Louis, MO, USA), human anti-mouse polyclonal pRb and β-actin antibodies (Cell Signaling Technology Inc., Danvers, MA, USA), human anti-rabbit monoclonal CDK4 antibody (Cell Signaling Technology, Inc.) overnight at 4 ̊C.

Techniques: Western Blot, Expressing